Growth Hormone
Sermorelin
The oldest of the growth-hormone-boosting peptides, with the longest track record. Often used as a gentler first step before people move to combinations like CJC-1295 and Ipamorelin. Still not well studied for general use beyond specific medical conditions.
Older analog — the gentler, more established alternative to the CJC-1295/Ipamorelin combo.
How well studied
Tier Guide: A = Well studied, B = Some good studies, C = Early evidence & D = Barely studied
Tested in people, but in smaller or fewer studies. A decent picture, just less certain.
How it works
Gives the pituitary gland a short, natural nudge to release growth hormone — similar to CJC-1295, just shorter-lived.
A shorter fragment that stimulates natural pituitary GH release, similar concept to CJC-1295 but shorter-acting.
Reported benefits
- Supports natural GH release with the longest track record of use in this category
- Considered a gentler starting point than CJC-1295/Ipamorelin
Who it's typically used for
Timeline to results
Dosage
No established self-administration dose for wellness use.
Side effects
- Injection site reactionsreported
- Flushingreported
- Elevated IGF-1 — theoretical hormone-sensitive tissue concernmonitoring-relevant, unresolved
Getting it in the UK
Still legal for a doctor to prescribe, but it hasn't been officially approved for this specific use. Uncommon, and comes down to a specialist's own judgement.
MHRA: the UK government body that checks a medicine is safe and actually works before doctors are allowed to prescribe it.
Content freshness
- Last reviewed
- 11 Aug 2026
- Regulatory status last checked
- 11 Aug 2026